
What does -prazole mean?
The -prazole stem marks a proton pump inhibitor. Why irreversible binding makes the effect outlast the drug, why dosing is before food, and the CYP2C19 trap.

The -prazole stem marks a proton pump inhibitor. Why irreversible binding makes the effect outlast the drug, why dosing is before food, and the CYP2C19 trap.

The -azepam and -azolam stems mark benzodiazepines. Why frequency rather than duration of channel opening makes them safer than barbiturates, and which are safe in liver disease.

The -dipine stem marks a dihydropyridine calcium channel blocker acting on vessels rather than the heart. Why that causes ankle oedema and reflex tachycardia.

The -terol stem marks a beta-2 agonist. Why the same receptor causes bronchodilation, tremor and low potassium, and why a long-acting one is never used alone in asthma.

The -floxacin stem marks a fluoroquinolone inhibiting DNA gyrase. Why tendon rupture, QT prolongation and the chelation interaction all follow from the class.

The endings mark the organism that produced the antibiotic, not how it works. Why gentamicin and erythromycin are spelled differently and share nothing else.

Stems are assigned by mechanism, so -olol, -pril and -sartan predict the target before you memorise anything. How the system works and exactly where it stops.