
Mechanisms, explained simply10 min read
What does -prazole mean?
The -prazole stem marks a proton pump inhibitor. Why irreversible binding makes the effect outlast the drug, why dosing is before food, and the CYP2C19 trap.

The -prazole stem marks a proton pump inhibitor. Why irreversible binding makes the effect outlast the drug, why dosing is before food, and the CYP2C19 trap.

The -floxacin stem marks a fluoroquinolone inhibiting DNA gyrase. Why tendon rupture, QT prolongation and the chelation interaction all follow from the class.

Why the mnemonics fail: inhibition is immediate and induction takes days, prodrugs reverse the direction, and the FDA defines strong inhibition by a measured AUC change.

Intestinal CYP3A4 inhibition explained, which statins are affected, and the exam trap. Safety-first pharmacology in six minutes.